How to use Technologies offered

A search for a cancer, preclinical stage, synthetic opportunity would use the selection "Therapeutics, Diagnostics" in 'Sector', 'Cancerous, neoplasmatic' in 'Disease Category', 'Drugs, Small Molecule' in 'Technology' and 'Preclinical' in 'Development Stage'.

Selection of 'Enabling Technology, Platform Technology' in 'Sector' will identify all kinds of research technologies that can be used in more areas of life sciences than pharmaceuticals only.

Each technology profile gives the name of a company or academic institute as source of the offer, and a link allowing to contact the potential licensor. In most cases a profile includes a pdf covering the available non-confidential information as well as detailed contact data.

Registered users can create non-public notifications profiles which will inform them about new 'Technologies Offered' entries fitting their needs as specified. In addition these profiles allow them to filter the available information more comfortably.


Cholesterol emulsion and supplementary food for the treatment of Smith-Lemli-Opitz syndrome

Organization name

Clinic Invent



The Smith-Lemli-Opitz syndrome is a heredi-tary autosomal recessive malformation syn-drome based on a metabolic disorder of cho-lesterol biosynthesis. As a result, there is a deficiency of cholesterol and at the same time increase of 7-dehydrocholesterol (7-DHC), resulting in the affected patients with many health impairments.

The current standard therapy consists in the administration of cholesterol in water or oil, for example as a suspension. Due to the low solu-bility of cholesterol in both liquids, a sediment are often formed, whereby only a small part of the amount of cholesterol administered to the patient can be ingested and absorbed, while the majority of the cholesterol is excreted un-used.

Therefore, there is a further need of cholester-ol-containing compositions that can be used for an optimized intake of cholesterol.


The present technology offer relates to edible emulsions of particular composition and their use in medicine. Especially, for the treatment of diseases associated with a decreased cho-lesterol level, such as the Smith-Lemli-Opitz syndrome. Further, a process for producing such emulsions has been developed.

Advantages of the invention

  • Emulsions can be prepared to contain a defined amount of cholesterol.
  • Properties of the emulsions can be adapted to the application according to the respective patient requirements.
  • Lowering the 7-DHC level.
  • High storage stability with cooling.

Patent situation

Patent application filed in Germany.

To view the contact information, attachments and url of this profile you have to login into your account or register a new account: Login Register

Your feedback to "Cholesterol emulsion and supplementary food for the treatment of Smith-Lemli-Opitz syndrome"


latest entries

latest entries