Biodegradable nano- and meso-polymer particles for protecting the pulmonary surfactant of the lung
TransMIT Gesellschaft für Technologietransfer mbH
This innovation concerns biocompatible polymeric nano-, meso-and micro-polymer particles which are able to bind pathogenic proteins that penetrate into the lining layer of the lung. These particles can be used for the prevention and treatment of lung diseases which are associated with an increased lung surface tension and a damage of the pulmonary surfactant.
Unique selling points
The interception of pathogenic proteins is based on a size effect (in comparison to the lung surfactant), electrostatic interactions and an entropy/enthalpy effect, which allows for the first time an efficient protection or even regeneration of the lung surfactant.
The market potential for this innovation can be deduced from the total number of patients affected by acute lung injuries or severe acute respiratory syndrome. The achievable patient number amounts to 0.5 million cases per year in the EU, North America and Japan. Due to the severity of the disease, the high death rate, and a lack of alternative treatment concepts can be assumed that the new technology will be well established in the market.
This results in a potential market volume of up to 1 billion Euros per year.
The next step would be the development of the medical product until approval with an industry partner.