How to use Technologies offered
A search for a cancer, preclinical stage, synthetic opportunity would use the selection "Therapeutics, Diagnostics" in 'Sector', 'Cancerous, neoplasmatic' in 'Disease Category', 'Drugs, Small Molecule' in 'Technology' and 'Preclinical' in 'Development Stage'.
Selection of 'Enabling Technology, Platform Technology' in 'Sector' will identify all kinds of research technologies that can be used in more areas of life sciences than pharmaceuticals only.
Each technology profile gives the name of a company or academic institute as source of the offer, and a link allowing to contact the potential licensor. In most cases a profile includes a pdf covering the available non-confidential information as well as detailed contact data.
Registered users can create non-public notifications profiles which will inform them about new 'Technologies Offered' entries fitting their needs as specified. In addition these profiles allow them to filter the available information more comfortably.
Modulation of ß-Catenin signalling for the treatment of cardiovascular diseases
ß-catenin, one of the key regulator molecules of Wnt signalling pathway has been described within several clinical syndromes like cancer diseases.
The present technology provides ß-catenin as a target in cardiovascular diseases. In vivo data derived from transgenic mouse models indicate a hypertrophy and enforcement of myocard action indicating a therapeutic use in cardiac repair upon nuclear depletion of ß-catenin.
In-licensing of know-how and IP for target and validation, (pre-)clinical testing and development of therapeutics.
A priority establishing European Patent is pending (confidential).
To view the contact information, attachments and url of this profile you have to login into your account or register a new account: Login
Please click here to log in to view the complete profile.