Peptide Drug Bioconjugations
Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule. The field of bioconjugation has had a considerable impact on academic research, clinical diagnostics and the production of therapeutics.Peptides are an important type of molecules for derivatization by bioconjugation. Peptide–drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage of improving therapeutic potential of drugs. Both linear and cyclic peptides have been explored as trafficking moiety due to ease of synthesis, structural simplicity, and low probability of undesirable immunogenicity.
Research is ongoing for the development of new drug delivery systems for targeted drug delivery. Peptides derived from sequence of cell surface proteins have shown potent binding affinity to the target cell surface receptors. Equipping peptides-drug conjugates with target cell specific ligands like EGF and RGD peptides can provide a solution for selective and targeted delivery.
Creative Peptides provides a one-stop solution for all of your peptide-drug bioconjugation needs. Our custom peptide synthesis, modification, and conjugation services involve chemical modification of peptide at highly specific sites. This allows for the elegant attachment of drugs or bioactive molecules though a wide variety of coupling techniques.
Creative Peptides gives you the best quality in peptides bioconjugation chemistry in the industry by implementing our state-of-the art peptides synthesis platform. Peptide synthesis, modifications, and conjugates produced at Creative Peptides have substantial purity. Each peptide-drug conjugate is meticulously monitored during synthesis and controlled according to our quality assurance and quality control standards.