How to use Technologies searched

A search for a company looking for a cancer, preclinical stage, synthetic opportunity would use the selection "Biomedicine, Diagnostics" in 'Sector', 'Cancerous, neoplasmatic' in 'Disease Category', 'Drugs, Small Molecule' in 'Technology' and 'Preclinical' in 'Development Stage'.

Selection of 'Enabling Technology, Platform technology' in 'Sector' will identify all kinds of searches for technologies that can be used in more areas of life sciences than pharmaceuticals only.

Each search profile gives the name or a short description of the company behind the search, and a link allowing to contact your potential licensee.

Registered users can create non-public notifications profiles which will inform them about new Technologies Searched entries fitting their expertise as specified. In addition these profiles allow them to filter the available information more comfortably.

Name

Basilea is seeking partnerships in drug resistance and dermatology

Organization name

Basilea Pharmaceutica business development

Profile

Basilea Pharmaceutica Ltd. is an independent biopharmaceutical company focused on new antibacterial and antifungal agents to fight drug resistance and on the development of dermatology drugs.

Basilea's objective is to maintain a continuous pipeline of innovative candidates to meet the clinical need for products that have distinct advantages over available therapies, such as greater efficacy (e.g. cidal activity), especially against resistant organisms, and better safety, particularly decreased toxicity and risk of drug-drug interactions.

Basilea┬┤s core competencies in anti-infective research are genomics, enzyme kinetics, assay development to facilitate high-throughput screening, microbiology, medicinal chemistry and preclinical PK/PD modelling.

Their approach to generate a continuous pipeline of innovative products is based on:

  • focused optimization of compounds that belong to successful antibacterial classes,  
  • discovery of novel classes of antibiotic directed at new targets by screening compound libraries and microbial fermentation broth extracts, and by structure-based drug design,
  • modification of under-exploited antibacterial classes,  
  • and selective in-licensing and in-house optimization of validated lead compounds   

Basilea also possesses considerable assets in dermatology, including a collection of more than 300 retinoid and vitamin D analogs, and has extensive medicinal chemistry expertise in this field. These resources are being systematically explored using a network of collaborations to pursue research opportunities for several dermatological indications.

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