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Lilly is looking for opportunities in Cardiovascular Diseases

Organization name

Global External Research & Development Lilly Research Laboratories Eli Lilly and Company


Cardiovascular Diseases

The vision at Lilly Research Laboratories, of which Global External R&D is a part, is a commitment to discovering, developing and acquiring innovative medicines to improve outcomes for individual patients.

Lilly products are well established in many global markets, including the United States, Japan, the European Union, Canada, Australia and New Zealand. In addition to these geographies, these small and large molecules span the therapeutic area spectrum including cardiovascular diseases. With their partners, they plan to further our presence in this key therapeutic area and in these geographies.

They are particularly interested in:

  • Cardiovascular (CV) Event Reduction — defined as secondary prevention, patients with CV disease, acute/sub-acute and tailored chronic therapies.
  • Risk Factor reduction through lipid / metabolic therapies
    • Therapies that effect HDL, high triglycerides and LDL
    • Therapies that effect lipids and have other metabolic or vascular benefits
    • Selected plaque stabilization mechanisms
  • Other Inflammatory Vascular Disease Indications
    • Large vessel disease (abdominal aortic aneurysm)
    • Small vessel disease (peripheral arterial disease)
  • Stroke Prophylaxis Associated with Atrial Fibrillation
  • Chronic Heart Failure
    • Novel mechanisms

Currently out of scope:

  • Disease Modification in Stable Angina
  • Resistant Hypertension(Pending EMEA guidance on the need for a MACE trial)
  • Acute CHF, acute stroke
  • Ventricular arrhythmias
  • Valvular heart disease
  • Acute MI/Myocardial protection and ischemia reperfusion
  • VTE therapies, VTE prophylaxis
  • Nutraceuticals/natural products including fish oils

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